Unsurprisingly, the 49ers lead the all-time series between these two teams. Surprisingly, they only lead 36-29 — a ...

San Francisco started off October on a hot note, with parts of the city registering temperatures as high as 95 degrees on an ...

San Francisco's Folsom Street Fair, one of the largest leather and kink festivals in the world, took over the SoMa ...

San Francisco has come to represent the challenges faced by many large U.S. cities struggling with the rising cost of living ...

Kamala Harris is the heir to a political lineage that dates back to a chain-smoking, hard-drinking and profane political ...

Concerns about housing and crime are dominating San Francisco's mayoral race, an election that gives voters a chance to ...

The race for San Francisco mayor is on and the top four candidates are making their case ahead of Election Day. Here's what ...

The race for San Francisco mayor is on and the top four candidates are making their case ahead of Election Day. Here's what ...

The sidewalks were getting busier in downtown San Francisco this week as Salesforce employees returned to working in the ...

Cardinals star tight end Trey McBride has been ruled out of their crucial Week 5 matchup against the San Francisco 49ers.

San Francisco 49ers' stars George Kittle and Fred Warner are dealing with injuries, and here is the latest on their playing ...

Before the season, NFL trade rumors had Cleveland Browns wide receiver Amari Cooper going to the San Francisco 49ers for ...